Why 1M lines in the bed file?

[utrivedi]

Hi,

I am working on human genome but bumped into the same issue of bed files not being compatible with the bam file as many others. From previous posts I figured out that I only require 1M random lines in the bed file. I wondered how these random set of coordinates will help in accurate coverage calculations for the whole genome.

I really appreciate any explanation you could provide for this.

Many thanks, Urmi