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Pneumonia-Revisions

Open pnrobinson opened this issue 1 year ago • 2 comments

Mondo term (ID Label) https://www.ebi.ac.uk/ols/ontologies/mondo/terms?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FMONDO_0005249

Pneumonia is a common acute respiratory infection that affects the alveoli and distal bronchial tree of the lungs. https://www.nature.com/articles/s41572-021-00259-0

  1. -- I do not think that bronchopneumia is a separate disease, it would be hard to draw the line clinically
  2. pneumonia of swine, mycoplasmal -- should not appear under human hierarchy
  3. anaerobic overlaps with gram negative, and in fact the most common anaerobes are gram negative
  4. bronchiolitis obliterans with obstructive pulmonary disease -- this is a bundled term, I think that the disease is bronchiolitis obliterans, see https://www.ncbi.nlm.nih.gov/books/NBK441865/
  5. eosinophilic pneumonia is not infectious.
  6. pleuropneumonia is aso bunded. Many cases of pneumomia have pleural involvement, I do not think this makes it a separate disease.
  7. recurrent pneumomia is not a well defined disease, it is a sequance of acute diseases or can be regarded as a phenotypic feature that may indicate immunodeficiency
  8. pneumocystosis should be a child of a new term fungal pneumonia Suggest restructruing

Pneumonia --infectious pneumonia --- bacterial --- viral ---fungal ---parasitic --non-infectious pneumonia --- eosinophilic pneumonia ---aspiration pneumonia ----Chemical pneumonia

Possibly the non-infectious branch should be placed under pneumonitis

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pnrobinson avatar Jul 12 '22 23:07 pnrobinson

Here is another paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471962/ they cite Harrisons -- Terms lobar or bronchopneumonia not recommended.

pnrobinson avatar Jul 13 '22 00:07 pnrobinson

related to https://github.com/monarch-initiative/mondo/issues/822

nicolevasilevsky avatar Aug 26 '22 01:08 nicolevasilevsky