SEPIO-ontology

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VIVO ontology and projects is concerned with udnderstanding what evidence exists to suggest a person has expertise, and what degree of expertise, in a particular subject. Consider if aspects of...

mbrush

In the course of writing the ticket below, I can to the conclusion that it is actually **not** useful to distinguish between a criterion being unmet due to insufficient data...

mbrush

Define rules for determining 'direction' of evidence provided by Criterion Assessments

2

In the ClinGen Interpretation data model that is currently being aligned with SEPIO, CriterionAssessments are assertions based on ACMG Criteria that are used as a first tier of evidence for...

mbrush

Modeling 'direction' of evidence as a relationship vs an attribute of the evidence line

1

SEPIO needs to be able to describe evidence 'direction' - to indicate when a particular line of evidence is supporting, refuting, or provides inconclusive information relative to a target assertion....

mbrush

Use of 'Activities' or 'Contributions' to describe and organize Entity provenance

2

Many efforts like ClinGen will have use cases that would benefit from explicitly describing the activities through which Entities in our model (Assertions, Supporting Information, Evidence Lines) are created. ClinGen's...

mbrush

The figure in the readme (https://github.com/monarch-initiative/SEPIO-ontology/blob/master/docs/SEPIO%20Wiki%201.jpg) is not in line with current thoughts on the overall model (at least with regard to discussions regarding the ClinGen interpretation model. Two things...

bpow

Hi! I was pretty excited to stumble across SEPIO and I was hoping to get some guidance on adopting SEPIO by sharing the following use cases: 1. **modeling evidence supporting,...

jhpoelen

Hello! Could you please descirbe "SEPIO" abbreiation plus add descitpion about meaning and possible applications of your ontology? Maybe provide some references.

gwpl