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convey PL ~ DP regression model

Open mlin opened this issue 4 years ago • 0 comments

To help with approximate reconstruction of genotype likelihoods from binned DP (when downstream tools strictly require them to be present even in non-variant cells):

  1. during encoding, calculate regression coefficients for PL[1] and PL[2] on binned DP
  2. include them in the output file, perhaps in the header (but that'd require a second pass)
  3. optionally use them to fill out approximate PL vectors during decoding

mlin avatar Nov 10 '20 02:11 mlin