RSoptSC
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Cell-cell communication and lineage inference for scRNA-seq data
RSoptSC ![](https://github.com/mkarikom/RSoptSC/raw/master/man/figures/logo.svg)
Updates
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Demo SoptSC at
vignette("Joost_et_al")
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Read the SoptSC article in NAR
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SoptSC is also available as a MATLAB package here
Installation
install.packages("devtools")
library(devtools)
install_github("mkarikom/RSoptSC")
Features
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Inference of cell-cell communication between single cells
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Integration of multiple analyses in a consistent mathematical framework: clustering, marker genes, pseudotime, and lineage inference
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Cell-cell similarity matrix construction to improve clustering
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NMF-based marker gene identification
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Prediction of the number of clusters present (via eigengap properties of the similarity matrix)
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Prediction of the initial cell in pseudotime
Documentation
Full details of RSoptSC and examples are available here.