Mikhail Shugay

Results 90 issues of Mikhail Shugay

Plot is not re-calculated correctly when uploading two chunks of samples with different max size

bug

AD -> top panel, WS ->left panel

[Gupta T. Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis. Cancer Cell . 2024](https://pubmed.ncbi.nlm.nih.gov/38744246/) --- A convenient way to browse the data is by using...

vdjdb-records-associations
vdj-10x-immudex

[Zhang et al. Enhanced CD95 and interleukin 18 signalling accompany T cell receptor Vβ21.3+ activation in multi-inflammatory syndrome in children. Nat Comm 2024](https://pubmed.ncbi.nlm.nih.gov/38762592/)

vdjdb-records-associations
vdj-10x

See if our epitopes, linked to, say A*02, can be presented by other alleles based on NetMHCpan or other epitope presentation predictor. This functional may be transferred to downstream VDJdb...

vdjdb-records-formatting&proofreading
vdjdb-build-summary

Check for useful papers and studies in McPAS, IEDB and other databases and run association pipeline for them.

vdjdb-records-meta-paper
vdjdb-records-associations

[subj.](https://podman-desktop.io/docs/migrating-from-docker)

vdjdb-maintainance
vdjdb-build-infrastructure

[Kirk et al. DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma. Cell Rep Med 2024](https://pubmed.ncbi.nlm.nih.gov/38508137) --- Need more info on actual peptideTCR(?),...

vdjdb-records-paper

[Roy P. et al. Identification of apolipoprotein B–reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4+T cells in multiple donors. Front Immunol 2024](https://pubmed.ncbi.nlm.nih.gov/38571941/)

vdjdb-records-paper
vdjdb-records-associations

Check [stcrdab](https://opig.stats.ox.ac.uk/webapps/stcrdab-stcrpred) and [PDB](https://www.rcsb.org/search?request=%7B%22query%22%3A%7B%22type%22%3A%22group%22%2C%22nodes%22%3A%5B%7B%22type%22%3A%22group%22%2C%22nodes%22%3A%5B%7B%22type%22%3A%22group%22%2C%22nodes%22%3A%5B%7B%22type%22%3A%22terminal%22%2C%22service%22%3A%22full_text%22%2C%22parameters%22%3A%7B%22value%22%3A%22%5C%22t-cell%5C%22%20receptor%20tcr%22%7D%7D%5D%2C%22logical_operator%22%3A%22and%22%7D%5D%2C%22logical_operator%22%3A%22and%22%2C%22label%22%3A%22full_text%22%7D%5D%2C%22logical_operator%22%3A%22and%22%7D%2C%22return_type%22%3A%22entry%22%2C%22request_options%22%3A%7B%22paginate%22%3A%7B%22start%22%3A0%2C%22rows%22%3A25%7D%2C%22results_content_type%22%3A%5B%22experimental%22%5D%2C%22sort%22%3A%5B%7B%22sort_by%22%3A%22score%22%2C%22direction%22%3A%22desc%22%7D%5D%2C%22scoring_strategy%22%3A%22combined%22%7D%2C%22request_info%22%3A%7B%22query_id%22%3A%22f5de3657a14b81a1670b1252242e7a17%22%7D%7D) to update [PDB_Database.txt chunk](https://github.com/antigenomics/vdjdb-db/blob/master/chunks/PDB_Database.txt) and address #360.

vdjdb-records-formatting&proofreading
vdjdb-records-dataset