Mihail Anton

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Just a note, the above is without having exposed a purpose-built API. Therefore, my recommendation would be to see that as a foundation to build a more compact and potentially...

Here is the link to the promised API https://metabolicatlas.org/api/v2/#/GotEnzymes

It sounds to me like this could also sit within `ecModels`, continuing the idea of separating GECKO as a tool from its applications. My attempt to solve the loading of...

> since the second request is always returned from **cache** On the latest Firefox (macOS) I do see the data _transferred twice_, so, as @kito-inv mentioned above, it's not cached....

Just to make sure, you ran the same code, including the same data (DLD1 from Hart2015 from within the `data/datasets` folder. Was this tINIT or the newer [ftINIT](https://sysbiochalmers.github.io/Human-GEM-guide/gem_extraction/)? Also, are...

> I'm sure I used the same code and data. This was tINIT. I only ran the code twice within 24 hours, and I believe that the Human-GEM version didn't...

@yangjingyu1108, here is a starting point for a longer discussion on the "consistency" of model contextualization/extraction algorithms that, e.g., use either random order of pruning reactions or random seeds in...

> It might be better to take steps by starting with adding a dedicated file for storing SMILES for prototyping, and merging to `metabolites.tsv` later. > I say the file...

Very good point @JonathanRob. I want to remember someone sharing a story about this, something like starting to map via SMILES because it was easier/more popular in other databases, and...