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Logistic mixed models?

Open cizydorczyk opened this issue 5 years ago • 3 comments

Just wondering if there are any plans to implement logistic mixed models (in addition to existing linear models) for association testing?

As the documentation mentions, using a linear model with logistic data can cause a loss of power, etc. As such, it would be great if pyseer had such a logistic mixed model implementation, as well.

Conrad

cizydorczyk avatar Jun 12 '19 18:06 cizydorczyk

We do plan on adding this in a future release - I wrote some prototype code to interface to such a model, but haven't had a chance to fully integrate this yet. I plan to add it before the end of the year.

johnlees avatar Jun 12 '19 18:06 johnlees

is adding logistic models still part of the plan?

sarapita avatar Mar 11 '22 10:03 sarapita

Realistically no, sorry, I don't see this being added to pyseer any time soon. I expect that pyseer will remain fairly frozen with its current set of features. You could try limix directly, which I think supports this. We may at some point in the future create a separate package with these kind of features, but that wouldn't be in the near future.

johnlees avatar Mar 11 '22 10:03 johnlees