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Computed features vs PC with new AnnData format

Open Soorya19Pradeep opened this issue 1 month ago • 2 comments

The code is modified to read from the zarrs with the new anndata format. @srivarra, can you let me know if there is a better way to do this?

@edyoshikun , I have computed the image features outside the library as I used the segmentations of G3BP1 for the image feature computation.

Soorya19Pradeep avatar Nov 20 '25 18:11 Soorya19Pradeep

@srivarra , the computed feature set depends on the organelle data. At this point I keep changing the set as I work with different organelles. I think a tool like CellProfiler can compute a 1000-feature list, which can be further filtered for the most significant features. I haven't implemented anything like that yet. That is when it will be ready to be added to AnnData as it will be a more constant list.

Soorya19Pradeep avatar Nov 25 '25 21:11 Soorya19Pradeep

@Soorya19Pradeep

the computed feature set depends on the organelle data. At this point I keep changing the set as I work with different organelles.

Ah gotcha, so keep the csv output for quick iterations / until we know exactly what features we want?

srivarra avatar Nov 25 '25 21:11 srivarra