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Summarize methylation statistics from bisulfite DNA-seq libraries
Some recent BS-seq programs store methylation information in a SAM tag. One example is Bismark. A flag for --methylation
would activate routines for summarizing:
- [X] Cycle-specific CpG cytosine methylation
- [x] Cycle-specific cytosine conversion
- [ ] Methyl-C content percent per read
Since there are only a few data formats for representing methylation data from bisulfite sequencing, flags for --bismark
, --bsmap
etc.. might be useful.