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Possibility to keep off-targets list of gRNA in repeats ?

12

Hi, We are currently working on identifying gRNA sequences targeting sub-families of transposable elements. The purpose is to test "consensus" sequences that we identified to show that these sequences are...

pebonte

Error when putting the genome onto the ramdisk

6

Hello, and many thanks for writing CRISPOR!! I have been able to locally install CRISPOR on an Ubuntu 18.04 OS, in order to run it from the command line. I...

Lukas-1

summary

1

From Jubina: First of all, the library dependencies of libssl, libpng and libcrypto create error. so I made a symbolic link in order for the program to pick the correct...

maximilianh

From Jubina Benny: INFO:root:converting genePred to segment names: cat /tmp/MusaPhahang/MusaPhahang.gp | awk 'BEGIN {FS=OFS=" ";} // { gsub(" " , "_", $1); gsub(" ", "_", $12); print }' | genePredToBed...

maximilianh

Local Instalation

12

Hi, I'm trying to install the local version of CRISPOR, but getting the following error. Can you help me? python crispor.py sacCer3 sampleFiles/in/sample.sacCer3.fa sampleFiles/mine/sample.sacCer3.tsv -o sampleFiles/mine/sample.sacCer3.mine.offs.tsv INFO:root: * running on...

DaniPaulo

I ran into a problem that the deep-cpf1 score generated from the command line is different from the results of the web version

8

Hello, I ran into a problem that the deep-cpf1 score generated from the command line is different from the results of the web version( http://crispor.tefor.net/ ). Have you ever encountered...

guomaoping

Bumps [requests](https://github.com/psf/requests) from 2.28.0 to 2.31.0. Release notes Sourced from requests's releases. v2.31.0 2.31.0 (2023-05-22) Security Versions of Requests between v2.3.0 and v2.30.0 are vulnerable to potential forwarding of Proxy-Authorization...

dependabot[bot]

Bumps [oauthlib](https://github.com/oauthlib/oauthlib) from 3.2.0 to 3.2.2. Release notes Sourced from oauthlib's releases. 3.2.2 OAuth2.0 Provider: CVE-2022-36087 3.2.1 In short OAuth2.0 Provider: #803 : Metadata endpoint support of non-HTTPS OAuth1.0: #818...

dependabot[bot]

Bumps [certifi](https://github.com/certifi/python-certifi) from 2022.6.15 to 2022.12.7. Commits 9e9e840 2022.12.07 b81bdb2 2022.09.24 939a28f 2022.09.14 aca828a 2022.06.15.2 de0eae1 Only use importlib.resources's new files() / Traversable API on Python ≥3.11 ... b8eb5e9 2022.06.15.1...

dependabot[bot]

Bumps [pillow](https://github.com/python-pillow/Pillow) from 9.1.1 to 9.3.0. Release notes Sourced from pillow's releases. 9.3.0 https://pillow.readthedocs.io/en/stable/releasenotes/9.3.0.html Changes Initialize libtiff buffer when saving #6699 [@​radarhere] Limit SAMPLESPERPIXEL to avoid runtime DOS #6700 [@​wiredfool]...

dependabot[bot]