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The relationship between cell type association and heterogeneity

Open AI-10 opened this issue 1 year ago • 1 comments
trafficstars

hi, thanks for this powerful tool!

I did some analyses and have some questions about the interpretation of the results.

Is the discussion of within-cell type heterogeneity premised on that the cell type is significantly associated with the trait?

I found some cell types that were significantly associated with MDD, but the heterogeneity was significant for some other cell types.

AI-10 avatar Aug 18 '24 05:08 AI-10

Sorry I missed this. Yes, that's how we generated figure 3 in the original paper. We think the signals are more robust this way.

martinjzhang avatar Oct 30 '24 16:10 martinjzhang