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version question about meryl

Open bucongfan opened this issue 10 months ago • 1 comments

Hi,

Thank you for this awesome software!

During the kmer calling process, I noticed that different versions of Meryl take significantly different amounts of time. Version 1.3.1 is almost three times faster than the version I installed in 2020 using conda, which is version 1.7 showed by --version. However, when using the same dataset, I found that the size of the database differs, even though it generates the same kmer count (verified by using to_hist_for_plotting.sh, which shows the total count is the same).

I'm curious, are there any significant differences between the versions, or are they generally compatible?

I also noticed that the Meryl databases created by different versions seem to have the same structure. Can I use these db, even if they were built with different versions of Meryl?

bucongfan avatar Apr 07 '24 20:04 bucongfan

I noticed the compatibility of different Meryl versions you mentioned regarding Canu 1.8. If incompatible db are used, will the current version of Meryl throw an error directly?

bucongfan avatar Apr 07 '24 20:04 bucongfan