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Chromosome sizes for epigenetics files differ from CHM13_v2.0 or are unavailable

Open chrarnold opened this issue 11 months ago • 0 comments

I noticed that for some of the epigenetics files that are linked here (https://s3-us-west-2.amazonaws.com/human-pangenomics/T2T/CHM13/assemblies/annotation/regulation), such as the file chm13v2.0_CGI.bed, the chromosome sizes seem to differ from the CHM13 2.0 coordinates.

$ grep "#sequence" chm13v2.0_CGI.bed
##sequence-region chr11 1 135125159
...
##sequence-region chrY 1 62453557

These sizes differ from the chromosome sizes for 2.0, I just verified with the published .fa and .fai file in the same AWS server.

For the BigBed files posted here (https://s3-us-west-2.amazonaws.com/human-pangenomics/index.html?prefix=T2T/CHM13/assemblies/annotation/regulation/ENCODE/macs2_peak), I dont see any reference chromosome sizes in the files, how to verify that these files do or do not have the same problem?

chrarnold avatar Jan 27 '25 09:01 chrarnold