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batch effect

Open drosop opened this issue 8 months ago • 3 comments

Hi,

Im working on bulkATAC data. The experiment was run in two batches and when I made the PCA plot, the data is separated by batches indicating strong batch effect.

Can I use these samples with batch effect for running tobias?

Is there any way to remove to batch effect prior to tobias? I used limma to correct for batch effect for differential accessiblity analysis.

Thank you,

drosop avatar Oct 27 '23 19:10 drosop