The role of cobra in classic virome pipeline

[xjhzjucas]

Hi Linxing: Thank you for developing this nice tool! I am curious about what's the functions does COBRA have in the classic virome pipeline as it's a new software. For example, I used MEGAHIT to get contigs from metagenome reads, and then I used geNomad to identified the viral contigs from the total contigs, and then if I use COBRA in the follow step (i.e. put the geNomad results:<prefix>_summary/<prefix>_virus.fna as the input of COBRA) , does COBRA help me to bin the identified viral contigs together to get a higher completeness here? Can it work before or after geNomad well? I read about that COBRA can identify more circular viral genome and huge phage. Can I consider COBRA as a binner tool or a circular/huge phages identifier? Thanks!