PureCN
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Whitelist for homozygous deletions
The current cutoff for homozygous deletions is large because we rarely see such huge deletions at MTAP/CDKN2A. Might be better to decrease the default and add a whitelist of known deletions.
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[ ] Query TCGA for most common deletions.
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[ ] Provide whitelist for hg19/hg38
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[ ] Use size distribution of whitelist for finding good size cutoffs, understand how SNP6 cutoffs translate to small targets with 150-200kb off-target bins.
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[ ] Do not count known deletions to max.homozygous.loss cutoffs.