Using this package for PacBio or EM_Seq data

[olaraym]

Please can I use this package on any of Pacbio or EM_seq-based methylation data?

[olaraym]

thanks in anticipation of your response @liguowang

[liguowang]

Looks like you cannot use cpgtools for DNA methylation data generated from Pacbio. If my understanding is correct, Pacbio methylation data is mostly binary calls (methylated for unmethylated).

Don't know about EM-Seq, if it is conceptually similar to RRBS (i.e., generate methylated reads, unmethylated reads), you can use cpgtools.