subsampling vs coverage thresholds

[r-mashoodh]

hi,

thanks for developing this -- it looks really useful.

I had more of conceptual question. In the popoolation manuals it always suggests subsampling pileups to create equal coverage. Is that something that is still necessary/useful here? And if so, how does one decide either on the subsampling value, or min/max coverage?

cheers and many thanks in advance.