Big FDR values for 42 sample

[AndreaPeC]

Hello, Thanks so much for this tool!!!

I’m having some issues understanding why I’m getting such big FDR values, I’m currently working with 42 samples, 2 groups and 1000 permutations and I’m getting that go from 0.5 to 0.99. At the beginning I thought it may be because of the number of permutations but I have also tested for 10, 20 and 100, and the FDR values stay on the same range, only the number of DMR changes.

Hope you can help me understand why this is happening?

Thank you!!!