protein-protein interaction interface scoring

[dhiraj82]

Hi I have a bunch of protein-protein complex of a target with binders designed using bindcraft. I want to repredict/validate them using boltz and rank them using at least some criteria so I can make more educated decision about which binders to order for experimental testing. are there any score from boltz output that I can rely on?

Thank you Dhiraj

[gcorso]

Hi Dhiray,

Unfortunately, we there is no module trained to predict protein-protein affinity currently in the repo, but we are working on it!

Gabriele

[navvye]

You can use APPT in the meantime - https://github.com/Bindwell/appt