John Sirois

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The OP is not solved since it relies on functionality forthcoming in #2299; so I'll leave this issue open but stop progress / un-assign for now.

> I tried out the newish --exclude feature here and it does not work since it only excludes post resolve; i.e.: after [download dists, build wheels, install wheels], which is...

@cognifloyd you can always use a vcs requirement pointing to your fork + patch. Since pyinotify is a sdist anyhow, this is next to no skin off your back IIUC...

> If there's something PEX could do to work around that awful (or "aggressive" as you put it so nicely) `setup.py`, like patching pip somehow, that would be amazing! Alright...

Alrighty, at long last I think this can be considered complete. With the improved `--exclude` released in [2.4.0](https://github.com/pex-tool/pex/releases/tag/v2.4.0), the OP example can be satisfied and this is now enshrined in...

Broken off of #2277 to make way for an `--inject-env` fix and a new `--exclude` feature.

As discussed in #2287, the prior practice of maintaining a release ticket for each release served little purpose. I've modified this issue to instead just track higher priority items to...

I am no longer using a backlog system - trying to just go ~inbox 0; so I'll close this.

Alright @PhoenixHe-NV, `--system-site-packages` support is now available in Pex 2.16.0.