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[Question] Would clusters of proteins from MMSEQS2 be considered orthologs?

Open jolespin opened this issue 3 years ago • 1 comments

Let's say you had 100 strains of a particular species. If you did an all-vs-all clustering of proteins, would those resulting clusters be considered orthologs?

jolespin avatar Aug 02 '22 00:08 jolespin

No, we do not filter for orthology in our clustering. They are homologous.

martin-steinegger avatar Aug 03 '22 10:08 martin-steinegger