vclust

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Thanks for the great tool!

Currently, vClust only allows users to compute all-v-all ANI. While this is very useful for clustering, there are also instances where this is not necessary and a query v reference approach would be more efficient.

For example, if I assemble viral sequences and am interested in quickly comparing them to a public database (i.e. IMG/VR) to assess novelty, it would be much faster to align only my query sequences to IMG/VR rather than performing an all-v-all alignment.

Is this something vClust is already capable of, or something that is planned for the future?