GLUE

GLUE copied to clipboard

Dear Authors,

Hi all, I have added functions to implement the functions of integrating gene expression information and protein information from CITE-seq data. I have offered two options to model protein data, either using 1. NBmixture or 2. Normal Distirbution after preprocessing with CLR. It seems that the later option works better. I also provide a method to create the gudiance graph between genes and proteins.

Sincerely, Tianyu

Hi, sorry for my late reply. I have made the modification based on your comments. For NBMixture model, I used categorical and nb distribution from torch to implement. Please let me know if you have other questions.