Gui can be opened more than once causing issue ( can't close gui plus errors pop up every try )
Open GUI, then open it again to reproduce.
Error: 
As exe, the error is : 
Welp, that's weird but this has however occured for me aswell. It can RARELY happen if the program has been running for a long time. Since it happens to rarely I have no idea why or how it happens. If you could give me some more information about your system, admin priveleges and Columbus settings it would help.
The way I had it happen was simply run Columbus, then right click the tray and open settings. Repeat. 2 X settings are open.
Close 1, ok. Close the second, error and it remains open until you close Columbus and relaunch. There isn't any check to prevent a second settings window from opening if one already is opened.
Oh! I see. I updated Columbus with the fix, please let me know if it worked :)