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Include SVs into somatic report configuration.

Open axelgschwind opened this issue 4 years ago • 1 comments

Currently, somatic structural variants are chosen by hand.

Like germline SVs, somatic SVs should be imported into NGSD and the user should be able to select a SV for the somatic report configuration.

axelgschwind avatar Jul 22 '20 12:07 axelgschwind

  • [x] Config fields for somatic SV-config - exclude reasons [artefact, unclear effect, other], description, comment, overwrite fields (of germline), rna information [confirmed, not confirmed, RNA data not usable]

  • [x] Create tables in NGSD

  • [x] improve annotation of SVs:

    • [x] Breakpoint genes split by breakpoint
  • [x] add import option for somatic SVs to NGSDAddVariantSomatic

  • [x] GSVar: improve SV-Widget for somatic

    • [ ] ~~target region filter auch auf Breakpoint_Genes anwenden (basierend auf Gennamen, automatisch von kleinen Varianten übernehmen)~~
    • [x] The SV type (BND, DUP, DEL, ....), SomaticScore, the 4 Tum_PR/SR_ref/alt, Flags,
  • [x] Report: add table to somatic report (see Sorin E-Mail from 14.03.24)

  • [x] add Tests:

    • [x] NGSD function
    • [x] somatic report

Ott-Alexander avatar Mar 12 '24 10:03 Ott-Alexander