megSAP
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Improve PRS computation
- [ ] allow reference base to be effect allele (required for some lifted SNPs)
- [ ] adapt megSAP conversion script
- [ ] adapt
VcfCalculatePRS
to handle this case (- [ ] checkVcfCheck
)
- [ ] add additional output for
VcfCalculatePRS
to export TSV with all found variants, allele counts... - [ ] adapt
calculate_prs_distribution.php
to exclude certain disease groups
- [ ] PGS file format not valid
- [ ] validation of all variants where AF doesn't match