Iván Pulido

Results 102 issues of Iván Pulido

From the `perses` side of things we noted a discrepancy when analyzing the Nonbonded forces in our test systems. Original issue in perses: https://github.com/choderalab/perses/pull/1124 A table summarizing it is as...

bug

Instead of forcing the perses `AtomMapper`, we should allow users to specify mapping dictionaries that could be created with external tools in our pipelines. This is related to https://github.com/choderalab/perses/issues/1204

enhancement :sparkles:

Since the RCSB is officially dropping support for PDB files in favor of using PDBx/mmcif formatted files, I think we should consider making sure we support this format. I suspect...

enhancement :sparkles:

From https://github.com/choderalab/openmmtools/pull/544#issuecomment-1071113024 We need to double check how imaging of complex is handled.

## Description Adds handling of max temperature parameter from input yaml file with CLI. ## Motivation and context We need to be able to specify the maximum temperature from input...

As part of our big refactor we are planning on using [`gufe`](https://github.com/OpenFreeEnergy/gufe) objects as base objects for most of the things we do. Writing a protein mutation protocol for [`alchemiscale`](https://github.com/openforcefield/alchemiscale)...

future
priority: medium
effort: medium

Currently perses REST capabilities are not being used in the small molecule pipeline from CLI. One quick way to do this is passing a configuration option from the YAML file...

bug :bug:

While trying to run the new edges in the https://github.com/openforcefield/protein-ligand-benchmark/tree/new-perses-edges dataset I noticed that at least one edge is failing when creating the mapping with the following error: ```python ---------------------------------------------------------------------------...

potential bug :thinking: :bug:

We want to write the PDBs for the initial and final states of the simulation in the subdirectory where the openmm systems live (XML subdir).

enhancement :sparkles:

We should be able to integrate other atom mappers such as the TimeMachine mapper or similar, that we could use in perses for doing the mapping.

enhancement :sparkles: