Manuel Holtgrewe
Manuel Holtgrewe
What about the following. We create a native plugin system based on [extism](https://extism.org/). This allows writing plugins in wasm. We pass data through interfaces as JSON for simplicity. We can...
@tedil this should not be forgotten
@tedil what's the status?
Refseq does not have chrmt transcripts. We should write out ensembl transcripts in this case also to the refseq column... Further, our tx data is not on the latest cdot...
It may be counterintuitive, but chrmt variants are annotated on m. coordinates only. Note that in jannovar we annotated with the gene name as the symbol. https://hgvs-nomenclature.org/stable/background/refseq/ Clinvar agrees https://www.ncbi.nlm.nih.gov/clinvar/RCV000144018/...
https://github.com/varfish-org/mehari-data-tx/pull/37 That's the best I can do on mobile.
OK, but the data release to automerge. https://github.com/varfish-org/mehari-data-tx/pull/36 This should hopefully enable prediction for all chrMT transcripts. Please try out. @gromdiom could you deploy the new mehari-data-tx release to reev?
@coderabbitai full review
@stolpeo just taking the CodeRabbit AI for a test drive here just for fun ;-)
> I had started https://github.com/varfish-org/annotation-zoo a while ago, but that repo got stalled, since I was busy with DHA stuff. It would be great if we could put repro stuff...