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is it possible to use DeepAccNet with protein complex?

Open weikang1214 opened this issue 2 years ago • 1 comments

Hi Hiranumn,

Nice project! I am trying to use DeepAccNet to score a protein complex model, however, it only scored the first chain. I wonder if it is OK to combine multiple chains into a single chain before feeding it to DeepAccNet and how reliable the results will be.

Thank you! :)

weikang1214 avatar Apr 11 '22 02:04 weikang1214

maybe you can give this pdb as a total template to af2,and predict with seq, the pae and lddt score can more accrately tell you how confident this template is, which i believe dan can not do this to a complex since it is not traning on that.(a special use for af2 which you can find on sergey ochinvkov's tweet).

Wangchentong avatar May 10 '22 07:05 Wangchentong