Priors for split vs paired discordant ratios

[cc2qe]

We can calculate an estimate for PE/SR ratio based on the read length and insert size. SVs that deviate from this ratio (e.g. few or none of an evidence type) will have lower confidence. SVs in the correct ratio (both type of evidence) have higher confidence.

In addition, for joint SV genotyping, we can adjust these ratios based on the observation in the proband sample (sample the SV was discovered in).