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Which side is supported in fold-back inversion events?
Hi!
I'm trying to understand the difference between ++ and -- strandedness in BND's with both break-ends on the same chromosome. From here I understand that these are one-sided inversions. Unlike inversions with support on both sides (INV), which seem to always have the ++ orientation, these one-sided inversions can be either ++ or --. I suspect that this should indicate which breakend has support. Wonder if you guys can clarify?
Thanks!