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Request: AnnotaTR dosage min/max instead of sum

Open raphaelbetschart opened this issue 1 month ago • 0 comments

Hi, I was playing around with TRTools to run a GWAS. AnnotaTR is working very nicely together with plink to run a GWAS. I was wondering if it would be possible to calculate dosage in various ways: Currently only the sum of the alleles is calculated, would it also be possible to annotate the VCF or PLINK files with the number of repeat of the shorter or longer allele? Something like this: --dosage-calculation:

  • sum: Summed number of repeats
  • min: Number of repeats on the shorter allele
  • max: Number of repeats on the longer allele

Best, Raphael

raphaelbetschart avatar Jan 22 '25 14:01 raphaelbetschart