Gregor Sturm
Gregor Sturm
When attempting to broadcast a function to a data array which has a different return type than input type this fails with: ``` MethodError: Cannot `convert` an object of type...
I have the following plot and want to want to compare `HER2+` to `triple-negative` for each gene (41BB, CD8A, ...) using ggpubr's `stat_compare_means`. In the end I want to have...
Follow-up PR on #814, to discuss its behavior and eventually disable the dry-run mode.
### Description of feature IMO autoencoder-based sequence embedding has a huge potential for finding similar immune receptors, potentially improving both the speed and the accuracy compared to alignment-based metrics. In...
### Description of feature I have been playing with omniscope's COVID dataset that provides 8M TCR receptors. By doing so, I identified several bottlenecks that make working with >1M cells...
### Description of feature The define_clonotypes function scales badly. There are two problems with it * it could be faster (while it relies heavily on numpy, there are parts implemented...
### Description of feature Loading AIRR data with 1.5M rows takes ~10 minutes. This is not too bad, but could be made less annoying * Make validation optional (I expect...
From https://github.com/mamba-org/mamba/issues/739 I understood that in https://github.com/mamba-org/mamba/pull/894 a lockfile mechanism was introduced that should enable multiple `mamba create` commands to run in parallel. However, this doesn't seem to work for...
I created a singularity container containing everything required to run the script. Maybe it's useful for others. It would even be possible to attach the container SIF-file as an asset...
Hi @swolock, thanks for this tool! It's blazing-fast and looks promising on the 10x PBMC data. However, when working on a larger dataset of T cells, the histograms don't have...