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Published 20 hours ago • verified publisher icon greenelab

New Paper (Other): Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England

Open marouenbg opened this issue 4 years ago • 1 comments

Title: Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England

General Information

Please paste a link to the paper or a citation here:

Link: https://www.medrxiv.org/content/10.1101/2020.12.24.20248822v1

What is the paper's Manubot-style citation?

Citation: @doi:10.1101/2020.12.24.20248822

Is this paper primarily relevant to Background or Pathogenesis?

  • [ ] Background
  • [x] Pathogenesis
  • [ ] Methods

Please list some keywords (3-10) that help identify the relevance of this paper to COVID-19

  • keyword 1 transmissibility
  • keyword 2 B1.1.7
  • keyword 3 SARS-CoV-2

Please note the publication / review status

  • [x] Pre-print
  • [ ] New Peer-Reviewed Paper
  • [ ] Peer-Reviewed Paper Pre-2020

marouenbg avatar Jan 18 '21 00:01 marouenbg

Which areas of expertise are particularly relevant to the paper?

  • [ ] virology
  • [ ] epidemiology
  • [ ] biostatistics
  • [x] immunology
  • [ ] pharmacology
  • [ ] other:

Summary

Suggested questions to answer about each paper:

  • What did they analyze? Estimated transmissibility of the B1.1.7 SARS-CoV-2 Variant in England.

  • What methods did they use? Mathematical modeling.

  • Does this paper study COVID-19, SARS-CoV-2, or a related disease and/or virus? This paper is about the evolution of SARS-CoV-2 into a variant called B1.1.7

  • What is the main finding (or a few main takeaways)? This preprint suggests that the variant B1.1.7 is more infectious and outcompetes other variants by acquiring a competitive advantage.

  • What does this paper tell us about the background and/or diagnostics/therapeutics for COVID-19 / SARS-CoV-2? This paper tells us about the spread of the new variant B1.1.7 in England. Related to #776 , a mutation that increases the affinity of SARS-CoV-2 towards human ACE2 is present in this variant possibly because of selection pressure.

  • Do you have any concerns about methodology or the interpretation of these results beyond this analysis? None

Any comments or notes?

marouenbg avatar Jan 18 '21 01:01 marouenbg