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There are bugs in version 1.6

Open ColinR01 opened this issue 1 year ago • 3 comments

Have you checked the FAQ? https://github.com/google/deepvariant/blob/r1.6/docs/FAQ.md:

Describe the issue: When variant is not detected, the program will freeze in the last step;

Setup

  • Operating system:Centos7.6
  • DeepVariant version: 1.6
  • Installation method (Docker, built from source, etc.): singularity
  • Type of data: (sequencing instrument, reference genome, anything special that is unlike the case studies?) PACBIO-SMART;A reference sequence for a normal person;

Steps to reproduce:

  • Command: /bin/singularity run -B /work/:/work/ /work/deepvariant.sif /opt/deepvariant/bin/run_deepvariant --model_type=PACBIO --ref=human_geneA_reference.fa --reads=reference.align.bam --output_vcf=out.vcf --output_gvcf=out.gvcf --num_shards=32
  • Error trace: Last line: I0119 11:43:53.450599 47012502976320 call_variants.py:623] Complete: call_variants(Stuck at this step).

Does the quick start test work on your system? Please test with https://github.com/google/deepvariant/blob/r1.6/docs/deepvariant-quick-start.md. Is there any way to reproduce the issue by using the quick start?

Any additional context:

deepvariant_1.6.pdf

ColinR01 avatar Jan 19 '24 08:01 ColinR01

@ColinR01 ,

Is it possible to provide the input files to reproduce this result?

kishwarshafin avatar Jan 19 '24 15:01 kishwarshafin

I believe @kishwarshafin was able to reproduce the issue and is currently looking into a fix. Keeping this open for now.

pichuan avatar Jan 30 '24 03:01 pichuan

Hi @ColinR01 ,

Please try the following docker that has the patch incorporated that should fix your issue:

docker pull google/deepvariant:CL602468145
docker pull google/deepvariant:CL602468145-gpu

kishwarshafin avatar Feb 06 '24 00:02 kishwarshafin

@ColinR01 , Can you please try the v1.6.1 docker? If the issue isn't resolved, please feel free to reopen this bug.

kishwarshafin avatar Mar 19 '24 20:03 kishwarshafin