NTR - metabolism: [GDP-mannose biosynthetic process from glucose]

[rozaru]

Please provide as much information as you can:

• Suggested term label: GDP-mannose biosynthetic process from glucose

• ChEBI ID and label of the substance: Please ensure that the ChEBI ID corresponds to the physiological form (pH7.3) of the compound. In the ChEBI entry, pH7.3 compounds have a 'UniProt synonym', as in the example for mycophenolate has_primary_input CHEBI:4167 D-glucopyranose has_primary_output CHEBI:21168 GDP-mannose

• Definition (free text) The chemical reactions and pathways resulting in the formation of GDP-mannose from glucose.

• Reference, in format PMID:####### PMID: 21273394 PMID: 9287314

• Gene product name and ID to be annotated to this term In fly: Hex-A Hex-C Pgi Mpi Pmm2 Gmppa Gmppb

• Parent term(s) GDP-mannose biosynthetic process GO:0009298

• Synonym(s) (please specify, EXACT, BROAD, NARROW or RELATED) Other than the standard synonyms below

• Children terms (if applicable) Should any existing terms that should be moved underneath this new proposed term?

• Cross-references MetaCyc PWY-5659 (start with glucose 6-phosphate)

• Any other information Cells can make GDP-mannose from either mannose or glucose. Depending on the cells, glucose is the predominant source. Below is a schematic of the coverage of the new term compared to the already existing terms (the gene are from the fly).

Thank you

Rossana

@sjm41 @ukemi @deustp01

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• FOR ONTOLOGY EDITOR

• Logical definition

• • substance metabolic process: 'metabolic process' and ('has primary input or output' some [substance]
• • substance biosynthetic process: 'biosynthetic process' and ('has primary output' some [substance].
• • substance catabolic process: 'catabolic process' and ('has primary output' some [substance]

• Standard synonyms

• • substance metabolic process:
• • • EXACT: substance metabolism
• • substance biosynthetic process:
• • • EXACT: substance anabolism
• • • EXACT: substance biosynthesis
• • • EXACT: substance formation
• • • EXACT: substance synthesis
• • substance catabolic process:
• • • EXACT: substance breakdown
• • • EXACT: substance catabolism
• • • EXACT: substance degradation