go-annotation
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geneontology
This repository hosts the tracker for issues pertaining to GO annotations.
Dear all, The proposal has been made to obsolete GO:0043719 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity see https://github.com/geneontology/go-ontology/issues/28053 Experimental annotations that need to be reviewed are here: https://docs.google.com/spreadsheets/d/1DEPs9j_UqB4I5DQ1L5k0w4az3I79Q8XHQeeTX0cS7z4/edit?gid=0#gid=0 Impacted groups: TAIR 1 ----...
GO:0102203 brassicasterol glucosyltransferase activity GO:0102205 cholesterol alpha-glucosyltransferase activity GO:0102202 soladodine glucosyltransferase activity
Dear all, The proposal has been made to obsolete GO:0051507 beta-sitosterol UDP-glucosyltransferase activity GO:0051506 ergosterol UDP-glucosyltransferase activity GO:0051508 stigmasterol UDP-glucosyltransferase activity GO:0051509 tomatidine UDP-glucosyltransferase activity since these represent specific substrates...
Dear all, The proposal has been made to obsolete GO:0036531 glutathione deglycation see https://github.com/geneontology/go-ontology/issues/28116 Experimental annotations that need to be reviewed are here: https://docs.google.com/spreadsheets/d/1ZMkJTkcWSJjpReOF66DKfbX5l93LLvwWL7IxVoQWu_g/edit?gid=0#gid=0 Impacted groups: ParkinsonsUK-UCL 1 ---- Mappings...
Dear all, The proposal has been made to obsolete GO:0008997 ribonuclease R activity see https://github.com/geneontology/go-ontology/issues/28072 Experimental annotations that need to be reviewed are here: [LINK TO ANNOTATION REVIEW GOOGLE SPREADSHEET...
Dear all, The proposal has been made to obsolete GO:0097224 sperm connecting piece see https://github.com/geneontology/go-ontology/issues/28003 Experimental annotations that need to be reviewed are here: https://docs.google.com/spreadsheets/d/1DPf99uAxMhMDrX254b3YMvNigqhF0BPqx3g3jOurQ3w/edit#gid=0 Impacted groups: MGI 4 UniProt...
* **InterPro ID / label** GO:0016973 | poly(A)+ mRNA export from nucleus | IEA with IPR045114 * **Example sequences with problematic annotation (ID + gene/protein name):** https://www.yeastgenome.org/locus/S000003844#go https://www.pombase.org/gene/SPAC1B3.08 * **Description...
Dear all, The proposal has been made to obsoleteGO:0060520 activation of prostate induction by androgen receptor signaling pathway see https://github.com/geneontology/go-ontology/issues/28041
GO:0032429 regulation of phospholipase A2 activity GO:1900138 negative regulation of phospholipase A2 activity GO:0032430 positive regulation of phospholipase A2 activity GO:0032431 activation of phospholipase A2 activity
TL;DR - there are uniprot KW and EC annotations to this family that contradict the literature. I'll take yeast RAD26 as an exemplar here, but similar patterns are seen in...
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This repository hosts the tracker for issues pertaining to GO annotations.