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verified publisher icon fritzsedlazeck

How to specify pedigree information in multisample calling mode?

Open tnguyengel opened this issue 2 years ago • 2 comments

How do we specify pedigree information for families or trios for multisample calling mode?

tnguyengel avatar Aug 21 '23 18:08 tnguyengel

you cannot right now. Its a gernal merge meaning that it just merges across the samples. The GT field and SUP_VEC field will help you navigate which variants are e.g. de novo in a trio setting or somatic between tissues. Hope that helps Fritz

fritzsedlazeck avatar Aug 21 '23 18:08 fritzsedlazeck

Do you suggest merging different families or different populations in separate batches so that we can tweak the merge settings to be more aggressive within a family or within a population?

tnguyengel avatar Aug 21 '23 18:08 tnguyengel