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AlleleFraction filter in sniffles

Open netwon123 opened this issue 1 year ago • 0 comments

Hello, I've been working on a batch of ont data. in order to avoid the bias of DEL and INS, i want to balance their count by AlleleFraction. I found the af dict in the src/sniffles/postprocessing.py, so i added a few lines of code as a condition judgment, if af was less than a certain value I mark it as "GT". Structurally I got more GT marks, but the count of other variants(DUP, INV) also increased. I don't know why. So I came to you for help!

netwon123 avatar Jun 27 '23 02:06 netwon123