Sniffles icon indicating copy to clipboard operation
Sniffles copied to clipboard

Adding .g.vcf support

Open bartcharbon opened this issue 1 year ago • 1 comments

For the pipeline we are using Sniffels in it would be really convenient to have genomic vcf support.

Are there any plans to ass gvcf support in the future?

bartcharbon avatar Mar 16 '23 09:03 bartcharbon

Hey there, gVCF doesn't work on SV. However, sniffles2 implements something similar. You need to use the snf file tag on the per single sample calling and then the merge implemented in sniffles with these snf files directly. This will produce a fully genotyped VCF File. The command line documentation shows you how to do that. Cheers Fritz

fritzsedlazeck avatar Mar 16 '23 12:03 fritzsedlazeck