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R wrapper of BCFTools score

Open sounkou-bioinfo opened this issue 7 months ago • 2 comments

Hi,

Thank you again for this great set of tools !

In the interest of promoting the adoption of gwas-vcf and my first time experience with your plugins (very fast !!), i made a package to bundle the plugin functions to be distributed in a R package https://sounkou-bioinfo.r-universe.dev/RBCFLib.

I made some minor change to make the bundling possible using an approach similar to the pysam strategy. As of now this provide a wrapper to bcftools and score, but the goal is to facilitate BCF centric classes for gwas data i/o in a more idiomatic R ways (data frame like objects)

I though this might be of interest to some R users of the tools and may be worth mentioning in the readme.

Best wishes !

sounkou-bioinfo avatar May 19 '25 21:05 sounkou-bioinfo

Thank you @sounkou-bioinfo and I am glad the tools are useful to you. In the past I have often used a combination of bcftools query to output tables from VCFs and data.table::fread() to quickly load them into a data frame structure in R but clearly your tools go way beyond that

freeseek avatar May 20 '25 15:05 freeseek

i might still do the data.table::fread() for the data loading bit if the other strategies (ALTREP, memory map files, delay arrays, etc) i am trying out don't pan out or would be much more involved than the scope of this package Thank you again

sounkou-bioinfo avatar May 20 '25 17:05 sounkou-bioinfo