Increase speed of spot detection

[jstitlow]

Compute time on our HPC ranges from 1-30 minutes, depending on the number of spots.

Any general advice on how to speed this up? I've split up the analysis using the multiprocessing module, but returns are rather limited.

Is there GPU implementation for bigfish?

Data and computer specs 2047x2047x20 px
100-10000 spots per image (Intel(R) Xeon(R) CPU E5-2660 v3 @ 2.60GHz) x 30 processors 115GB RAM

Also opening a separate issue to discuss the possibility of analyzing images by cell instead of whole frame, and analyzing super-expressing cells in analogue mode (or ignoring these cells to process separately).

Cheers, Josh