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Add Protein Proximity Index

Open stelfrich opened this issue 8 years ago • 6 comments

There was a call for implementation of the protein proximity index in Coloc_2 on the Coloc page of the ImageJ/Fiji wiki that I have removed:

Maybe someone wants to add PPI to the Coloc_2 plugin? original article here

Further information about PPI / PPA can be found on a dedicated PPI/PPA page by the authors.

stelfrich avatar Mar 18 '16 09:03 stelfrich

Any particular reason to remove it? Why not leave the idea open? Current implementation is in matlab. Few people will.use it due to the activation barrier. An implementation in Coloc plugin of Fiji makes it available to many with no effort on their part, so more citations for the authors. Disagree?

chalkie666 avatar Mar 18 '16 12:03 chalkie666

I rolled back your edit because it removed useful information. Let's talk about what your motives and ideas are here before we agree on any changes. OK?

chalkie666 avatar Mar 18 '16 12:03 chalkie666

Let's talk about what your motives and ideas are here before we agree on any changes. OK?

Hey @chalkie666. First of all, sorry for changing the entry before asking, the roll-back is fine with me.

My motive was to remove an implementation (namely Coloc_2) specific comment from the rather general part about colocalization analysis on that wiki page. Plus, there is an Ideas list that I would find more appropriate for such a call for implementation. But on the other hand, this ideas list refers to GitHub, where I have opened an issue.

All in all, I thought that this comment would be better suited for a GitHub issue where it is more likely to get picked up by a developer.

Why not leave the idea open? Current implementation is in matlab. Few people will.use it due to the activation barrier. An implementation in Coloc plugin of Fiji makes it available to many with no effort on their part, so more citations for the authors. Disagree?

Totally agree! That's why I have opened an issue here, because development is happening here..

stelfrich avatar Mar 18 '16 13:03 stelfrich

Hi @stelfrich Ok, thats all good. On the fiji / imagej wiki, Lets leave the text and link to the paper describing PPI, and ADD the link to the webpage http://www.anes.ucla.edu/~wuyong/PPI/index.html but as you suggest the coloc2 specific statement inviting developers to implement it., as now that request lives in this issue. ? Can you do that? or shall I?

I will label / tag this issue as a feature request "enhancement" to implement PPI in coloc2, and put all the relevant links and info here.... which i guess already happened! So thats good.

chalkie666 avatar Mar 18 '16 14:03 chalkie666

Can you do that?

I have added the link to the author's page. Feel free to change it, if you don't like it :+1:

stelfrich avatar Mar 18 '16 14:03 stelfrich

@stelfrich Looks good! thanks!

chalkie666 avatar Mar 18 '16 19:03 chalkie666