Protein generation around active site without specifying residue numbers

[RobinFeng123]

Hi, I am trying to use ESM to generate a protein backbone around an active site. I would like to know if it is possible to do the structure generation without specifying where the active site amino acids are in the sequence.

In other words, is it possible to only supply active site amino acid coordinates and the expected length of the final protein, and let the program decide by itself the residue number? Thanks