Is if possible for VCF-Simplify to convert non-dosage vcf to dosage vcf?

[ConnieXuhm]

Dear developer, I am trying to acquire the dosage VCF file converted from .gen format. However, qctools and other conversion can only output the non-dosage VCF, which cannot meet my demand of the following investigation. Then I find out that maybe Pysam can do this, but I am not quite familiar with the complex code. I want to know if this VCF-Simplify can achieve this function? Many thanks! Hope for your reply!

[everestial]

Hi @ConnieXuhm

Please share your VCF file (both dosage and non-dosage) so I can tell if it can do what you want it to do.

For a more controlled and custom VCF parsing you may use https://github.com/everestial/vcfparser but this application is still waiting for few more changes and updates.

Let me know if you have any other questions.