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Improve documentation on `cnvkit call` and the use of VCFs

Open tskir opened this issue 4 years ago • 0 comments

Currently, some aspects of how VCF samples are loaded and processed are a bit obscure in the documentation. This especially applies to things like BAF rescaling and LOH detection; see for example https://github.com/etal/cnvkit/issues/601#issuecomment-835861846.

It seems like a good idea to restructure and clarify the parts related to VCF, how the samples are treated, how the maths of BAF rescaling and LOH detection works, etc.

tskir avatar May 09 '21 18:05 tskir