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Consider adding ECO classes to describe the evidence (assays) for observable outcomes

Open jmillanacosta opened this issue 1 year ago • 1 comments

Some classes and properties from the Evidence and Conclusion Ontology (ECO) could be added to the ontology to support linking observable outcomes to their evidence (an assay, a reference, etc.). I see a direct application in the SbD4Nano assertion network, where an assay involving certain assay specifications, a material, a cell line/animal model, etc. is supporting evidence for an assertion (e.g., dose correlates with toxicity).

https://www.ebi.ac.uk/ols4/ontologies/eco

curation method for the assertions:

manual assertion
http://purl.obolibrary.org/obo/ECO_0000218

An assertion method that involves human review.

A manual assertion could be based on evidence that is generated by and interpreted by a human or it could involve human review of computationally generated information.

the assay has role:

experimental evidence used in manual assertion
http://purl.obolibrary.org/obo/ECO_0000269

A type of experimental evidence that is used in a manual assertion.

the assertion is a:

conclusion based on data (Imported)
http://purl.obolibrary.org/obo/OBI_0001909

An information content entity that is inferred from data.

jmillanacosta avatar Feb 16 '24 09:02 jmillanacosta