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Published 20 hours ago • verified publisher icon enanomapper

Term for reactive oxygen species assay

Open vedina opened this issue 8 years ago • 5 comments
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The ENM ontology has term for Oxidative stress, but not for a specific assay. The preferred name of the assay is DCFH2-DA (recommended by 10.3109/10715761003709802) , synonyms are DCFDA and H2DCFDA .

vedina avatar Sep 23 '17 16:09 vedina

Does it have a BAO term?

egonw avatar Sep 23 '17 17:09 egonw

Could not find BAO term.

@pennym might help as well.

vedina avatar Sep 23 '17 18:09 vedina

BAO has a term "oxidative stress assay" BAO_0002168 (which is in ENM) which could be a parent term for various specific assays such as the DCFH2-DA.

pennym avatar Sep 25 '17 06:09 pennym

A related question. Is it possible to find the relationship between properties and assays, e.g.

  • (assay) DCFH2-DA is measuring (property) Oxidative stress
  • (assay) A is measuring (property) Y
  • (assay) A is measuring (property) Z
  • (assay) B is measuring (property) Y

I've asked similar question a while ago for phys-chem, but also relevant for all type of assays.

vedina avatar Sep 25 '17 06:09 vedina

That is explained in the BAO paper, I think: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-12-257

egonw avatar Sep 25 '17 07:09 egonw